Feeding Studies

• Estimation of the expected intake and evaluation of nutritional significance
• Analysis of expected benefits and/or adverse reactions
• Determination of the efficacy, nutritional value or wholesomeness of GM feed
• Obtainment of data concerning the resistance of newly expressed protein to proteolytic enzymes
• Nutritional assessment of GM food/feed
• Assessment of the effects on animal health

Methods:

• Feeding trials on swine, chicken and ruminants under controlled housing conditions (determination of feed uptake, development of body weight, feed utilization, estimation of digestibility, animal health).
• Subchronical systemic toxicity (oral intake) (EN DIN ISO 10993-11, Pkt. 6.7.1, guinea pigs)
• Repeated dose 28-day oral toxicity study in rodents (OECD Guideline 407)