Toxicology

• Investigation of the toxicity of a newly and/or differently expressed protein and other identified new constituents as well as the consequences of any genetic modification
• Testing of the whole GM food/feed
• Repeated dose toxicity studies

Methods:

• Chemical, physico-chemical and physical analysis methods
• Testing for genotoxicity, cancerogenicity and reproduction toxicity (EN ISO 10993-3)
• Testing for cytotoxicity (EN ISO 10993-5)
• Testing for systemic toxicity (EN ISO 10993-11)
• Standardised, serum-free cultures of primary human and rodent hepatocytes
• Monitoring of hepatocellular functions
• Monitoring of hepatocellular viability in laboratories with certified Quality Management System